The 2024 WHO BPPL is a key tool for prioritising research and development investments and informing global public health policies to combat AMR. Gram-negative bacteria and rifampicin-resistant M tuberculosis remain critical priority pathogens, underscoring their persistent threat and the limitations of the current antibacterial pipeline. Focused efforts and sustained investments in novel antibacterials are needed to address AMR priority pathogens, which include high-burden antibiotic-resistant bacteria such as Salmonella and Shigella spp, N gonorrhoeae, and S aureus.
Collaborative use of population-level health data and artificial intelligence is essential for achieving precision health through a learning health system. Two groundbreaking initiatives—the European Health Data Space (EHDS), covering 449 million EU citizens, and Germany’s forthcoming Health Data Lab, providing access to data from 75 million insured individuals (90% of the country’s population)—offer unprecedented opportunities to advance digital health innovation and research with global impact.
Kidney and nerve tissue cells can form memories much like brain cells, one new study has found. Another recent study says that memories of obesity stored in fat tissue may be partly responsible for the yo-yo weight loss effect.
A new USC study suggests that gut imbalances in children with autism may create an imbalance of metabolites in the digestive system—ultimately disrupting neurotransmitter production and influencing behavioral symptoms.
The research, published in Nature Communications, adds to a growing body of science implicating the “gut-brain” axis in autism. The discovery raises the possibility of new treatment avenues. It’s an example of how research at USC, and other universities, drives innovation and leads to discoveries that improve lives.
“We demonstrated that gut metabolites impact the brain, and the brain, in turn, affects behavior. Essentially, the brain acts as the intermediary between gut health and autism-related behaviors,” said first author Lisa Aziz-Zadeh, a professor at the Brain and Creativity Institute at the USC Dornsife College of Letters, Arts and Sciences.
A car accident, football game, or even a bad fall can lead to a serious or fatal head injury. Annually, traumatic brain injuries (TBI) cause half a million permanent disabilities and 50,000 deaths. Monitoring pressure inside the skull is key to treating TBI and preventing long-lasting complications.
Most of these monitoring devices are large and invasive, requiring surgical emplacement. But Georgia Tech researchers have recently created a sensor smaller than a dime. The miniature size offers huge benefits.
“Surgery means extensive recovery time and can significantly impact patient health. Our system doesn’t require surgery because we use a conventional stent, the catheter, as a delivery vehicle,” said W. Hong Yeo, the Harris Saunders Jr. Endowed Professor and an associate professor in the George W. Woodruff School of Mechanical Engineering.
Developing humanoid robots, unravelling the complexities of AI, and the mysteries of consciousness.
Welcome to the North of Patient podcast — conversations on health[beyond]care — where we paint an inspired landscape of healthcare’s future through dialogues with creative and unconventional thinkers from around the world.
This week’s guest is the remarkable Dr. Suzanne Gildert. She’s a physicist, artist, and AI tech executive based in Vancouver on a mission to uncover the mysteries of consciousness and innovate unconscious AI.
In this episode, we dive into the groundbreaking advancements and pressing challenges in quantum computing, examining the transformative potential of these technologies to reshape our world. Beyond the science, we also explore the philosophical dimensions of AI consciousness, questioning whether AI can ever truly replicate human experience and identity.
Whar may happen when the first truly smart robots appear, based on brain emulations or ems. Scan a human brain, then run a model with the same connections on a fast computer, and you have a robot brain, but recognizably human.
Train them to do some job and copy it a million times: an army of workers is at your disposal. When they can be made cheaply. within perhaps a century, they will displace humans in most jobs. In this new economic era, the world economy may double in size every few weeks. Applying decades of expertise in physics, computer science, and economics. and use ofstandard theories indicate a detailed picture of a world dominated by ems.
Associate Professor of Economics, and received his Ph.D in 1997 in social sciences from Caltech. Joined George Mason’s economics faculty in 1999 after completing a two year post-doc at U.C Berkely. His major fields of interest include health policy, regulation, and formal political theory. Recent book: The Age of Em: Work, Love and Life When Robots Rule The Earth. Oxford University Press, 2016.
This talk was given at a TEDx event using the TED conference format but independently organized by a local community.
Here we look at the recent paper from the PEARL trial where rapamycin is being tested in healthy older adults for its safety and impact on markers of health…
For the first time, surgeons have successfully performed a remarkable new heart transplant in which the donor organ never skips a beat in the process, reducing the damage that can occur during such a complex operation. It ushers in a new era of more successful heart transplant surgery.
A team of surgeons at the National Taiwan University Hospital (NTUH) in Taipei undertook the revolutionary operation, during which the donor heart continues beating between the organ removal and transplantation stages. Traditionally, the donor heart would be removed and preserved in cold storage to reduce its workload – during this stage, it’s considered “ischemic time,” or the period during which the organ is cut off from blood supply. This comes with the risk of heart damage and rejection once it’s transplanted into a recipient.
When the heart is deprived of blood, ischemia – a shortage of oxygen – can damage its muscle tissue, or myocardium, reducing function and health once it is transplanted. While an organ set for transplant rarely endures more than a few hours in ischemic time, it can still lead to myocardial damage.
Measles, a highly contagious viral infection, continues to pose a significant public health threat worldwide. Despite the availability of effective vaccines, outbreaks persist, particularly in regions with low immunization rates. In 2023, the World Health Organization observed up to a 30-fold increase in measles cases in Europe. There are currently no treatment options for measles. Instead, patients must allow the virus to take its course and let the immune system naturally clear the infection.
Erica Ollmann Saphire, a structural biologist, and her research team at the La Jolla Institute for Immunology uncovered the structure of the measles glycoprotein and engineered a neutralizing antibody against it. This therapy could be implemented to manage measles outbreaks worldwide.
Researchers uncovered the structure of the measles fusion glycoprotein and identified a neutralizing antibody capable of decreasing its virulence.
